Five 7.5L bioreactors available for bioprocess development, scale-up parameter optimization, and tech transfer. Fully automated process control and fed-batch capable. Full and secure data capture.

Analytical lab for in-process and final sample analysis including gas chromatography, ultra-performance liquid chromatography, microscopy, spectrophotometry, stock culture storage, laminar flow hoods, incubators & shakers, and more.

Carry out process optimization (key variable screening and optimization) over a series of runs at the 7.5-L fermentor scale.

Collaborate with DBX on an experimental design plan and subsequent data analysis using experimental design software.

Identify key process variables: statistical significance and magnitude of impact.

Optimize key variables and determine impact on KPIs and product quality.

Two 7.5L, two 40L, one 75L, and two 300L bioreactors available for scale-up development and tech transfer in advance of piloting.

Isolated bioprocessing laboratories for focused scale-up development at each reactor scale.

Access to full analytical assays and laboratory equipment for scale-up development support.

3,000L bioreactor for pilot-scale production, optimization, and proof of scalability demonstrations.

Access to smaller-scale bioreactors for seed-train development and analytical equipment for in-process sample and final product characterization.

Flexible pilot-plant design with multiple utility drops for for additional unit-operations and process equipment installations.

Continuous centrifugation via disk-stack or decanter methods for processing between 300-3000L of fermentation broth.

Tangential-flow-filtration (TFF) via ceramic membranes allows concentration of target molecules.

Spray drying capabilities provide a final dried product powder at production scale.

Large scale lyophilization to provide freeze dried powder of temperature sensitive products or biomass.